Concurrent Estimation of Amlodipine Besylate, Hydrochlorothiazide and Valsartan by RP-HPLC, HPTLC and UV-Spectrophotometry
نویسندگان
چکیده
منابع مشابه
Estimation of Amlodipine Besylate, Valsartan and Hydrochlorothiazide in Bulk Mixture and Tablet by UV Spectrophotometry
A simple, precise, accurate and economic simultaneous UV spectrophotometric method has been developed for the estimation of amlodipine besylate, valsartan and hydrochlorothiazide in combination in bulk mixture and tablet. The estimation was based upon measurement of absorbance at absorbance maxima of 359 nm, 317 nm and 250 nm for amlodipine besylate, hydrochlorothiazide and valsartan in methano...
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A simple, specific, accurate and precise stability-indicating reversed-phase high-performance liquid chromatographic method was developed for simultaneous estimation of olmesartan medoxomile (OLME), amlodipine besylate (AMLO) and hydrochlorothiazide (HCTZ) in tablet dosage form. The method was developed using an RP C18 base deactivated silica column (250 × 4.6 mm, 5 µm) with a mobile phase cons...
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Background: The present work was undertaken with the aim to develop and validate a rapid and consistent RP-HPLC method in which the peaks will be appear with short period of time as per ICH Guidelines. Materials and Methods: The separation was achieved on a a stainless steel analytical column, Eclipse XDB plus C18 column (4.6 X 150 mm; 5 μm) in an isocratic mode. The mobile phase w...
متن کاملValidated Rp-hplc Method for Simultaneous Determination of Amlodipine, Hydrochlorothiazide and Valsartan in Pharmaceutical Formulation
An accurate, precise and reproducible reverse-phase stability-indicating HPLC method has been developed and validated for the simultaneous estimation of Amlodipine, Hydrochlorothiazide and Valsartan in combined dosage form. Separation was achieved using Phenomenex ODS 5μ, C18 column (250×4.6mm) and ACN : Methanol : 1% Triethylamine Buffer (39:26:35) as mobile phase which shows sharp and resolve...
متن کاملSimultaneous estimation of amlodipine besylate and nebivolol hydrochloride in combined dosage form by RP-HPLC
A simple, selective, rapid, precise and economical reverse phase HPLC method has been developed for the simultaneous estimation of Amlodipine Besylate and Nebivolol hydrochloride in pharmaceutical dosage forms. The method was carried out on a Luna C-18, 5 μ column with a mobile phase consisting of 0.005M ammonium acetate solution, acetonitrile and triethylamine in the ratio 60:40:0.1 (v/v) and ...
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ژورنال
عنوان ژورنال: Journal of Chromatographic Science
سال: 2013
ISSN: 0021-9665,1945-239X
DOI: 10.1093/chromsci/bms200